David Fedida's Lab

The Fedida laboratory is interested in problems of cardiac repolarization and rhythm that mainly involve the study of ion channels that regulate normal electrical activity and contractility in the heart. We also study ion channels in viruses that are important for their infectivity. Ion channels are small proteins that regulate the flow of charged cations and anions across cell membranes, and they are found in all cells throughout the body, and in all species in the Animal Kingdom. Come and have a look at some of the projects we are pursuing that involve the biophysics of potassium ion channels, how they are synthesized and transported to and from the cell surface, and how they open and close. As well, you can read about late sodium currents and heart failure, and viral ion channels from influenza A.